Molecular Details
DICL_CP_0306950
- nickel(2+)
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0306950
PubChem CID
Molecular Formula
Ni+2 Molecular Weight
58.693 g/mol
Synonyms/Alias
[Nickel(2+); Nickel cation; nickelous ion; NICKEL (II) ION; Nickel; ion (Ni2+); Ni2+; Nickel ions; Nickel(II) ion; Nickel(2+)ions; nickel(II) cation; Ni++; nickel(2+) ion; Nickel ion(2+); 14701-22-5; ...
InChI Key
VEQPNABPJHWNSG-UHFFFAOYSA-N
InChI
InChI=1S/Ni/q+2
IUPAC Name
nickel(2+)
CAS Number
7440-02-0
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
1 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 Ni 0 0 0 0 0 15 0 0 0 0 0 0
M CHG 1 1 2
M END
$$$$
Experimental Data
Activity Data
Target Ion Channel
Ryanodine receptor 1
Uniprot Accession Number
Function
Inhibitor
Species
Oryctolagus cuniculus (Rabbit)
IC50
N/A (Not available)
EC50
EC50: 6500 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
Not specified
Temperature
37 °C
Test Method
Efflux Assay ([86] Rubidium Ion)
Test Species
Not specified
Binding Information
Binding Site
Transmembrane domain
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
1
Rotatable Bonds
0
logP
-0.0025
Complexity
2.5
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0